schisto research community

content appropriate for schistosomiosis research

29 Apr

Lead Discovery Database at WHO

Published by MatTodd

Subject 

Miscellaneous

There's a new database from WHO for tracking new targets for drug discovery for neglected diseases. Not much there yet, but it's sure to grow.

Mat

07 Jan

Collaborative Drug Discovery UCSF/QB3-Hosted First Annual Community Users Meeting Agenda

Published by BarryBunin

Subject 

External News

Dear TSL Members,

 

You are invited to the first annual QB3-UCSF-CDD developing world disease research community meeting scheduled for March 5th 2007 at the UCSF Mission Bay Campus (details below and attached).  The collaborative community includes leading experts on developing world infectious disease research from Stanford, UCSF, UC Berkeley, UCLA, UW, SBRI, St. Jude CRH, U. Penn, Univ. of Sydney, and industry too.  

 

Collaborative Drug Discovery
First Annual Community Meeting

 

Monday, March 5th 2007 1:00-6:00 pm; Auditorium: J. David Gladstone Institute (1st Floor)

Hosted by Gladstone Institute and QB3 at the UCSF, Mission Bay Campus

Two major themes of this event are:

1)      Public-Private-Partnerships for Global Health Issues
2)      “Open” concepts for Collaborative Drug Discovery

Confirmed Speakers:
 

  • Dr. Christopher Lipinski, Pfizer, retired. (Keynote presentation)
  • Jim McKerrow, Professor, Dept. of Pathology, QB3 - UCSF
  • Matt Bogyo, Professor, Dept. of Pathology, Stanford Medical School
  • Andrej Sali, Professor, Dept of Biopharmaceutical Sciences, QB3 - UCSF
  • Dr. Anang Shelat, St. Jude Children’s Research Hospital
  • David Roos, Biology Professor, Univ. of Penn tentatively confirmed (Director, Penn Genomics Institute).

Symposium – Coffee/Snacks – Demos – Posters – Networking – Wine Reception

Registration is free. To register contact/RSVP to: kgregory@collaborativedrug.com.

Updates to Aza-Henry Catalysts

Published by MatTodd on 23 June 2006 - 6:54am

Just a quick update compiled by one of my students, Wing Yan, on some aza-Henry catalysts not included in the first post.
Cheers,
Mat

Aza Henry Catalyst Update 1

Aza Henry Catalyst Update 1

Published by MatTodd on 23 June 2006 - 6:50am

Aza Henry Catalysts Update 1

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Schisto Research Community
14 Jun

Site Level Email Subscriptions

Published by gtaylor

Configuring Your Subscription

You may choose to have daily email notifications sent to you from The Synaptic Leap. You must have a registered account first. Once you have have registered and are logged in, you can go to your personal user profile and hit the "my notify settings" tab. From there, you just enable the various buttons.

I configured my settings so that I get a headline, teaser and link for all new comments and articles posted on the site.

click the image to see a full size screen shot of

If no new posts are made, no email is sent. If multiple posts are made, you only receive one email summarizing the posts with links to each post. The email that is generated also includes a link back to your personal notification settings so that you can easily disable it anytime should you ever wish to.

Open Source Article Now Online

Published by MatTodd on 13 June 2006 - 1:20pm

The article on open source written by members of TSL is now online, and may be accessed here. The article is published in the Australian Journal of Chemistry, and the publishers (CSIRO, Australia) have agreed to provide the article as open access, so no subscription is required to download it.

We'd all be very interested in feedback and ideas on the very general points mentioned.

Cheers,

Mat

 

Subject 

Miscellaneous

Forums 

Q&A and Feedback
29 May

Jean-Claude's Reactions

Published by MatTodd

Subject 

Request for Help

Jean-Claude Bradley and his team over at UsefulChem have been having a go at two reactions that have relevance to generating drug candidates for malaria. Organic chemists should check out the site if they feel they can help with what's going on. The two reactions are firstly the conversion of adrenaline to catechol aldehyde:

UsefulChem Adrenaline Conversion

and secondly the Ugi synthesis of a DKP along the following lines:

 

UsefulChem DKP Ugi

The resources needed are your input into how to make these reactions go! The Usefulchem team are making good use of YouTube video feeds to provide extra information on what's going on with their attempts.

Cheers,

Mat

 

UsefulChem DKP Ugi

Published by MatTodd on 29 May 2006 - 11:38am

UsefulChem DKP Ugi


Subject 

Request for Help

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