You are invited to the first annual QB3-UCSF-CDD developing world disease research community meeting scheduled for March 5th 2007 at the UCSF Mission Bay Campus (details below and attached). The collaborative community includes leading experts on developing world infectious disease research from Stanford, UCSF, UC Berkeley, UCLA, UW, SBRI, St. Jude CRH, U. Penn, Univ. of Sydney, and industry too.
Collaborative Drug Discovery First Annual Community Meeting
Monday, March 5th 2007 1:00-6:00 pm; Auditorium: J. David Gladstone Institute (1st Floor)
Hosted by Gladstone Institute and QB3 at the UCSF, Mission Bay Campus
Two major themes of this event are:
1)Public-Private-Partnerships for Global Health Issues 2)“Open” concepts for Collaborative Drug Discovery
Confirmed Speakers:
Dr. Christopher Lipinski, Pfizer, retired. (Keynote presentation)
Jim McKerrow, Professor, Dept. of Pathology, QB3 - UCSF
Matt Bogyo, Professor, Dept. of Pathology, Stanford Medical School
Andrej Sali, Professor, Dept of Biopharmaceutical Sciences, QB3 - UCSF
Dr. Anang Shelat, St. Jude Children’s Research Hospital
David Roos, Biology Professor, Univ. of Penn tentatively confirmed (Director, Penn Genomics Institute).
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The article on open source written by members of TSL is now online, and may be accessed here. The article is published in the Australian Journal of Chemistry, and the publishers (CSIRO, Australia) have agreed to provide the article as open access, so no subscription is required to download it.
We'd all be very interested in feedback and ideas on the very general points mentioned.
Jean-Claude Bradley and his team over at UsefulChem have been having a go at two reactions that have relevance to generating drug candidates for malaria. Organic chemists should check out the site if they feel they can help with what's going on. The two reactions are firstly the conversion of adrenaline to catechol aldehyde:
and secondly the Ugi synthesis of a DKP along the following lines:
The resources needed are your input into how to make these reactions go! The Usefulchem team are making good use of YouTube video feeds to provide extra information on what's going on with their attempts.
