XRPD patterns of rac- and (R)- PZQAmine

Published by ndt228 on 6 October 2011 - 8:33pm
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PZQAmine XRPDs.pdf631.14 KB

The attached file contains X-ray powder diffraction patterns (XRPDs) for racemic and (R)- PZQAmine, as well as a mixture of the two.  These confirm that (as is often the case) the racemic compound and the single enantiomer have different crystal structures.  This is consistant with the phase diagram for PZQ Amine gathered from the melting point of mixtures of the two.
Thanks to Jana Galbraith (Almac Sciences Physical Sciences Dept) for recording these patterns.

Comments

MatTodd's picture

Nick. Very interesting. They're clearly different. I don't know how to "read" these structures, in order to see what they mean. Can structural information be gleaned?