A list of what's needed in the OSDD Malaria project
Community
malaria research communityMain: Comment/Analysis on Initial Bioactivity Data
We have some excellent first results. What to do next?
Resynthesis of TCMDC-123812 and TCMDC-123794 (ELN)
Need: advice on oxidation of pyrrole-3-carbaldehydes - here. Through a work-around, these syntheses are complete, but we could still ue advice on the step above. Done
General Analog Synthesis Planning
Need: Advice from med chemists on what to alter first - here.
Biological Evaluation of Initial Leads
Need: Advice on what kinds of biological evaluation are most desirable to validate the initial GSK leads - here.
Where Else Can we Access This Series?
Need: People with stocks of analogous compounds (i.e. members of the arylpyrrole series) to submit those compounds for screening. First possibility seen here.
We're compiling a list on OpenWetWare of compounds we would like to source.