HDAC inhibitor - sodium butyrate

24 Apr
Published by rayonsoleil

Sodium butyrate is an HDAC inhibitor -- very early & very recent cites --

J Biol Chem. 2007 Mar 30;282(13):9797-804. Epub 2007 Jan 24.Essential role of the JAK/STAT1 signaling pathway in the expression of inducible nitric-oxide synthase in intestinal epithelial cells and its regulation by butyrate.
Stempelj M, Kedinger M, Augenlicht L, Klampfer L.

Cell. 1978 May;14(1):105-13. Sodium butyrate inhibits histone deacetylation in cultured cells. Candido EP, Reeves R, Davie JR.

At Sullivan Lab, have you tried it and rejected it? Not yet tried it? Have reasons why it would not be suitable? Etc . . .