malaria research community

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UsefulChem DKP Ugi

Published by MatTodd on 29 May 2006 - 11:38am

UsefulChem DKP Ugi


Subject 

Request for Help

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TSL Images

UsefulChem Adrenaline Conversion

Published by MatTodd on 29 May 2006 - 11:36am

UsefulChem Adrenaline Conversion

Subject 

Request for Help

Image Galleries 

TSL Images
16 Feb

postgenomics.com

Published by marcius

This is really interesting. We certainly should try to get some of that working within TDI/TSL!

15 Feb

Gene Wiki Programmers Needed

Published by marcius

Subject 

Request for Help

TDI and TSL are in need of volunteers for the tools development within the Malaria community. You can read about the projects themselves here. So, what we need? Basically, we seek programmers with an interest of being part of a new community for BioMedical research. You would be applying your skills to develop tools that that should help advance the research of drug discovery for neglected diseases. This is something that you will feel good about! Gives good Karma!! The skills we are looking for in a volunteer in those projects are: - JavaScripting (in particular bookmarklets) - PHP programmer - MySql database experience - Familiarity developing Wiki-based tools a strong plus. - Familiarity with Drupal a strong plus - Familiarity with Trac a strong plus - Familiarity with Subversion a strong plus If you see that you would like to join, please do so by posting a comment to this entry! Thanks! marc

15 Feb

Some reading...

Published by marcius

Subject 

Miscellaneous

This is some reading you guys can do for getting familiarize on what we intend to do with TDI and TSL. I have posted in our respective web sites a one-page flyer with the very basic information:

TSL flyer
TDI flyer

You can also read the manuscript that started it all... Maurer, Arti Rai and Andrej Sali, PLoS Medicine 2004 and the commentary in The Economist about this manuscript.

Best,
Marc

14 Feb

European Parliament Hearing on Neglected Diseases

Published by marcius

Subject 

External News

European Parliament Hearing on Neglected Diseases - European Public Health Alliance:
The hearing seeks to highlight the need for better regulatory practices which are more suitably adapted to assessing therapeutic advances of new drugs, vaccines and diagnostics for neglected diseases. These diseases include AIDS, malaria, tuberculosis, leishmansis, Chagas disease and sleeping sickness.

14 Feb

TDI/TSL presented in Stanford University

Published by marcius

I have been introducing to the Stanford medical students what we do for the TDI and TSL initiatives. Achal S. Achrol is organizing a series of talks on Neglected Diseases and invited me to talk about our initiatives. You can see the slides here. I think that the audience was quite interested in the approach we are taking and hope we will have some of the folks joining TSL/TDI in a near future.

Achal and his collegues are very interested in implementing a wet-lab open-research community where scientists are able to share resources and information for a common goal... accelerating the drug discovery process for neglected diseases. There is certainly a good possibility of collaborating with them within the TSL initiative.

marc

11 Feb

Let's work together

Published by jcbradley

I have an organic chemistry lab available to carry out some of the synthetic work that needs to be done. As of this week our lab notebook is available online here http://usefulchem-experiments1.blogspot.com and discussions of our synthetic strategy is made public here http://usefulchem.blogspot.com

Our main focus is currently the synthesis and testing of anti-malarial agents. We would welcome input from the scientists on your team to help us contribute more effectively to this open science project.

Current Projects for Malaria

Published by marcius on 28 January 2006 - 11:31pm

Open source drug discovery project currently active - see GSK Arylpyrrole link below or this general intro page written at the start of the project and which lays out the Six Laws, or read about the current project status.

 

All malaria projects currently in process should be created as child pages to this page.  See the "add child" link at the bottom if you want to initiate a new open research project for malaria.

UsefulChem Project

Published by jcbradley on 21 December 2005 - 5:55pm

It is really nice to see more people attacking these important problems with open source strategies!

We also have a parallel effort UsefulChem and the project getting the most attention right now is on malaria as well.  We have a few hundred targets to synthesize based on a library provided by Find-A-Drug.  We are debating the best synthetic approach right now so if there are any chemists out there that have some contributions please post them on the blog.  We'll start the syntheses in a few weeks probably and will test them with in vitro assays. 

For the big picture view see http://usefulchem.wikispaces.com

For the main blog see http://usefulchem.blogspot.com

For our molecules of interest see http://usefulchem-molecules.blogspot.com

 

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