The Synaptic Leap

Glaxo allows access to 1000s of in house chemical to the public domain
 
http://www.guardian.co.uk/science/2010/jan/20/glaxo-malaria-drugs-public...

 http://www.pnas.org/content/early/2009/07/31/0907740106.abstract?sid=9765379a-8e16-4085-b4c9-5a5f126a0990 
 
 

 http://www.nature.com/nature/journal/v459/n7249/full/nature08104.html
 

 100% protective malaria vaccine
http://content.nejm.org/cgi/content/full/361/5/468 
Administering chloroquine before being exposed infected mosquitos, provides a vaccine that is 100% protective.
 

The development of falcipain-2 inhibitors as antimalarial agents is a collaborative Open Science project that we are joining.  Our research group studies the development of small molecule chemotherapeutic agents that are targeted to specific sites-of-action, at a microscopic level.  Falcipain-2 is a lysosomal enzyme of Plasmodium, the parasite that causes malaria.  Therefore, the ability to identify small molecule falcipain-2 inhibitors that accumulate in the lysosomes of the parasite while not accumulating in other parts of the human body is key if the chemotherapeutic agents under development are going to have potent antimalarial activity in vivo, with minimal side effects. 

THE SUBCELLULAR DRUG TRANSPORT LABORATORY (click here to visit our lab website)  

Hi all,

I would like to introduce my open-source project at Stanford, GemIdent:

http://www.gemident.com

http://en.wikipedia.org/wiki/GemIdent

GemIdent specializes in color image segmentation using supervised machine learning. For example, you can use it to locate and count cells in microscopic images:

GemIdent in action identifying cancer cells in a IHC-stained lymphnode image

I am a biochemist i have a good background on molecular biology. i would like to joint a research team to complete my PhD thesis.According to my accademic profile, i am able to work on many research areas like genetic diversity of schistosoma, efficacity of praziquantel, vaccine development against schistosoma spp. and so one.