MatTodd's blog

31 Jan

Misc articles

Published by MatTodd

Subject 

Miscellaneous

The Guardian Weekly's a lovely thing (particularly if you don't live in the UK). Two articles in yesterday's edition caught my eye.

24 Jun

Which Creative Commons Licence?

Published by MatTodd

Community 

general open research

We're drawing up a contract (with WHO and the ARC) to cover our new grant (and hence this site). Our business office would like to know which Creative Commons licence is most suitable. I was assuming Attribution 3.0 unported, since this allows sharing and remixing under attribution. On the face of it, a better alternative is Attribution-Share Alike 3.0 Unported, since this also requires that anyone using the research has to distribute their own work under a similar licence.

01 Jun

Funding Success for Open Source Project

Published by MatTodd

Community 

general open research

Subject 

Miscellaneous

We've been successful in securing a large government grant with an open source component. The 3-year project concerns the enantioselective synthesis of PZQ for a low price, with the World Health Organisation as partner. (PDF of the Uni Sydney outcomes is here). The funding comes from the Australian Research Council (the main government funding agency in Australia). We wrote the proposal emphasising the possibilities inherent in the open source approach to doing science, and we're very pleased that this was seen as positive by an official grant-funding agency. The funding will allow us to increase our efforts on using TSL to drive our project forward much faster.

21 May

Captcha issues

Published by MatTodd

Subject 

Rants

Thanks to the lovely spam bots, we had to activate our captcha module recently for new posts. Sadly most people (including me) couldn't read the characters, so we switched it off. While we work out what to do next, posts will temporarily be approved the old way. Hopefully the delay to posts being published should be minimal.

29 Apr

Lead Discovery Database at WHO

Published by MatTodd

Subject 

Miscellaneous

There's a new database from WHO for tracking new targets for drug discovery for neglected diseases. Not much there yet, but it's sure to grow.

Mat

10 Jan

Discussion on Ethical Pharmaceuticals

Published by MatTodd

Community 

general open research

Subject 

Miscellaneous

There was a report in a UK paper recently about an 'ethical pharmaceutical' approach to the production of new drugs, by the development of a patent-beating formulation of an existing compound. A discussion just started about this over here.

Mat

 

09 Jan

Open Source/Access Conference

Published by MatTodd

Community 

general open research

Subject 

Miscellaneous

A conference on open access/public knowledge projects is being held in Vancouver in July:

 http://ocs.sfu.ca/pkp2007/

It's interesting that this area has become large/mainstream enough that whole conferences are being devoted to it.

Mat

29 May

Jean-Claude's Reactions

Published by MatTodd

Subject 

Request for Help

Jean-Claude Bradley and his team over at UsefulChem have been having a go at two reactions that have relevance to generating drug candidates for malaria. Organic chemists should check out the site if they feel they can help with what's going on. The two reactions are firstly the conversion of adrenaline to catechol aldehyde:

UsefulChem Adrenaline Conversion

and secondly the Ugi synthesis of a DKP along the following lines:

 

UsefulChem DKP Ugi

The resources needed are your input into how to make these reactions go! The Usefulchem team are making good use of YouTube video feeds to provide extra information on what's going on with their attempts.

Cheers,

Mat

 

13 Mar

Ways to get involved and the Stanford Connection

Published by MatTodd

Community 

general open research

Subject 

Request for Help

A few of us have recently been talking via email about exciting developments at Stanford, and Ginger prompted me to post this on the site so others could comment. Here are the emails, edited down…

Marc originally visited Stanford to talk on what he's doing in the area of neglected diseases (http://www.salilab.org/~marcius/home/?page=talks). His talk was hosted by Achal Acrol.

In response, Achal wrote:

 

“I think it was clear that today's audience was very excited by your talk, and in general through my work with ADEM [Access and Delivery of Essential Medicines] I have noticed a growing interest here at Stanford among young researchers to carry out their training and career development in traditional ways while somehow finding some other way to simultaneously apply those skills/resources to affect some amount of positive change in the world.

 

I see probably the most effective collaboration of our efforts to be that while I continue to sign up labs that would be willing to provide certain resources and services, you could provide us with a wish-list of biological/chemical resources you would need to fully test any of the computational work your team does. In essence I would work to provide (the other 95%) 'beta-testers' that could respond to your computational biologists 'programming core' and perform the wet lab experiments and cell culture and in vivo experiments to verify in an open source manner the efficacy of those agents.

30 Jan

Minor glitches

Published by MatTodd

The feeds to papers on the left has gone, and the recent comments on the right is not updating. Also, for posting comments, there is the 'path alias' box. Could it be made a bit clearer what kind of information this is meant to contain - i.e. why it's useful?

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