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Identification and mechanistic understanding of dihydroorotate dehydrogenase point mutations in Plasmodium falciparum that confer in vitro resistance to the clinical candidate DSM265

CiteULike malaria tags - 9 November 2018 - 10:11am
ACS Infectious Diseases (30 October 2018), doi:10.1021/acsinfecdis.8b00211
John White, Satish Dhingra, Xiaoyi Deng, Farah El Mazouni, Marcus Lee, Gustavo Afanador, Aloysus Lawong, Diana Tomchick, Caroline Ng, Jade Bath, Pradipsinh Rathod, David Fidock, Margaret Phillips
Categories: malaria news feeds

Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development

CiteULike malaria tags - 1 November 2018 - 12:48pm
Scientific Reports, Vol. 8, No. 1. (25 October 2018), doi:10.1038/s41598-018-34078-3
Craig Duffy, Alfred Amambua-Ngwa, Ambroise Ahouidi, Mahamadou Diakite, Gordon Awandare, Hampate Ba, Sarah Tarr, Lee Murray, Lindsay Stewart, Umberto D’Alessandro, Thomas Otto, Dominic Kwiatkowski, David Conway
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A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

CiteULike malaria tags - 1 November 2018 - 11:56am
Malaria Journal, Vol. 17, No. 1. (26 October 2018), doi:10.1186/s12936-018-2532-x
Kimberly Breglio, Roberto Amato, Richard Eastman, Pharath Lim, Juliana Sa, Rajarshi Guha, Sundar Ganesan, David Dorward, Carleen Klumpp-Thomas, Crystal McKnight, Rick Fairhurst, David Roberts, Craig Thomas, Anna Simon
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Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites

CiteULike malaria tags - 18 October 2018 - 12:03pm
Nature Communications, Vol. 9, No. 1. (12 October 2018), doi:10.1038/s41467-018-06733-w
Hanwei Fang, Ana Gomes, Natacha Klages, Paco Pino, Bohumil Maco, Eloise Walker, Zenon Zenonos, Fiona Angrisano, Jake Baum, Christian Doerig, David Baker, Oliver Billker, Mathieu Brochet
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Within-host competition can delay evolution of drug resistance in malaria

CiteULike malaria tags - 11 September 2018 - 6:40pm
PLOS Biology, Vol. 16, No. 8. (21 August 2018), e2005712, doi:10.1371/journal.pbio.2005712
Mary Bushman, Rustom Antia, Venkatachalam Udhayakumar, Jacobus de Roode
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List of keywords of the INRMM meta-information database - part 23

CiteULike malaria tags - 7 September 2018 - 5:11pm
(February 2014)

List of indexed keywords within the transdisciplinary set of domains which relate to the Integrated Natural Resources Modelling and Management (INRMM). In particular, the list of keywords maps the semantic tags in the INRMM Meta-information Database (INRMM-MiD). [\n] The INRMM-MiD records providing this list are accessible by the special tag: inrmm-list-of-tags ( http://mfkp.org/INRMM/tag/inrmm-list-of-tags ).
Categories: malaria news feeds

Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei

CiteULike malaria tags - 6 September 2018 - 10:35am
Nature Microbiology (3 September 2018), doi:10.1038/s41564-018-0223-6
Robyn Kent, Katarzyna Modrzynska, Rachael Cameron, Nisha Philip, Oliver Billker, Andrew Waters
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Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution

CiteULike malaria tags - 30 August 2018 - 10:34am
PLOS Biology, Vol. 16, No. 8. (24 August 2018), e2006035, doi:10.1371/journal.pbio.2006035
Aude Gilabert, Thomas Otto, Gavin Rutledge, Blaise Franzon, Benjamin Ollomo, Céline Arnathau, Patrick Durand, Nancy Moukodoum, Alain-Prince Okouga, Barthélémy Ngoubangoye, Boris Makanga, Larson Boundenga, Christophe Paupy, François Renaud, Franck Prugnolle, Virginie Rougeron
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Fitness Loss under Amino Acid Starvation in Artemisinin-Resistant Plasmodium falciparum Isolates from Cambodia

CiteULike malaria tags - 24 August 2018 - 8:13am
Scientific Reports, Vol. 8, No. 1. (22 August 2018), doi:10.1038/s41598-018-30593-5
Duangkamon Bunditvorapoom, Theerarat Kochakarn, Namfon Kotanan, Charin Modchang, Krittikorn Kümpornsin, Duangkamon Loesbanluechai, Thanyaluk Krasae, Liwang Cui, Kesinee Chotivanich, Nicholas White, Prapon Wilairat, Olivo Miotto, Thanat Chookajorn
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Evolutionary history of human Plasmodium vivax revealed by genome-wide analyses of related ape parasites

CiteULike malaria tags - 23 August 2018 - 10:09am
Proceedings of the National Academy of Sciences (20 August 2018), 201810053, doi:10.1073/pnas.1810053115
Dorothy Loy, Lindsey Plenderleith, Sesh Sundararaman, Weimin Liu, Jakub Gruszczyk, Yi-Jun Chen, Stephanie Trimboli, Gerald Learn, Oscar MacLean, Alex Morgan, Yingying Li, Alexa Avitto, Jasmin Giles, Sébastien Calvignac-Spencer, Andreas Sachse, Fabian Leendertz, Sheri Speede, Ahidjo Ayouba, Martine Peeters, Julian Rayner, Wai-Hong Tham, Paul Sharp, Beatrice Hahn
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Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

CiteULike malaria tags - 20 August 2018 - 8:10am
Nature Communications, Vol. 9, No. 1. (17 August 2018), doi:10.1038/s41467-018-05652-0
Leila Ross, Satish Dhingra, Sachel Mok, Tomas Yeo, Kathryn Wicht, Krittikorn Kümpornsin, Shannon Takala-Harrison, Benoit Witkowski, Rick Fairhurst, Frederic Ariey, Didier Menard, David Fidock
Categories: malaria news feeds

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

CiteULike malaria tags - 26 July 2018 - 11:36am
The Lancet Haematology (July 2018), doi:10.1016/s2352-3026(18)30107-8
Carolyne Ndila, Sophie Uyoga, Alexander Macharia, Gideon Nyutu, Norbert Peshu, John Ojal, Mohammed Shebe, Kennedy Awuondo, Neema Mturi, Benjamin Tsofa, Nuno Sepúlveda, Taane Clark, Gavin Band, Geraldine Clarke, Kate Rowlands, Christina Hubbart, Anna Jeffreys, Silvia Kariuki, Kevin Marsh, Margaret Mackinnon, Kathryn Maitland, Dominic Kwiatkowski, Kirk Rockett, Thomas Williams, Amadou Abathina, Ismaela Abubakar, Eric Achidi, Tsiri Agbenyega, Mohammed Aiyegbo, Alex Akoto, Angela Allen, Stephen Allen, Lucas Amenga-Etego, Folakemi Amodu, Olukemi Amodu, Judith Anchang-Kimbi, Nana Ansah, Patrick Ansah, Daniel Ansong, Sampson Antwi, Thomas Anyorigiya, Tobias Apinjoh, Emmanuel Asafo-Agyei, Victor Asoala, Frank Atuguba, Sarah Auburn, Abdou Bah, Kariatou Bamba, Germana Bancone, Gavin Band, David Barnwell, Abdoulaye Barry, Evasius Bauni, Richard Besingi, Kalifa Bojang, Edith Bougouma, Susan Bull, George Busby, Abdoulie Camara, Landing Camara, Susana Campino, Richard Carter, Dan Carucci, Climent Casals-Pascual, Ndey Ceesay, Pa Ceesay, Tran Chau, Ly Chuong, Taane Clark, Geraldine Clarke, Ramou Cole-Ceesay, David Conway, Katharine Cook, Olivia Cook, Victoria Cornelius, Patrick Corran, Simon Correa, Sharon Cox, Rachel Craik, Bakary Danso, Timothy Davis, Nicholas Day, Panos Deloukas, Awa Dembele, Jantina deVries, Rajika Dewasurendra, Mahamadou Diakite, Elizabeth Diarra, Yaya Dibba, Andrea Diss, Abdoulaye Djimdé, Amagana Dolo, Ogobara Doumbo, Alan Doyle, Chris Drakeley, Eleanor Drury, Patrick Duffy, Sarah Dunstan, Augustine Ebonyi, Ahmed Elhassan, Ibrahim Elhassan, Abier Elzein, Anthony Enimil, Pamela Esangbedo, Jennifer Evans, Julie Evans, Jeremy Farrar, Deepika Fernando, Kathryn Fitzpatrick, Janet Fullah, Jacob Garcia, Anita Ghansah, Michael Gottleib, Angie Green, Lee Hart, Meike Hennsman, Tran Hien, Nguyen Hieu, Eliza Hilton, Abraham Hodgson, Rolf Horstmann, Christina Hubbart, Catherine Hughes, Ayman Hussein, Robert Hutton, Muntaser Ibrahim, Deus Ishengoma, Jula Jaiteh, Mariatou Jallow, Muminatou Jallow, Kebba Jammeh, Momodou Jasseh, Anna Jeffreys, Amie Jobarteh, Kimberly Johnson, Sarah Joseph, Dushyanth Jyothi, David Kachala, Dorcas Kamuya, Haddy Kanyi, Harin Karunajeewa, Nadira Karunaweera, Momodou Keita, Angeliki Kerasidou, Aja Khan, Katja Kivinen, Gilbert Kokwaro, Amadou Konate, Salimata Konate, Kwadwo Koram, Dominic Kwiatkowski, Moses Laman, Si Le, Ellen Leffler, Martha Lemnge, Enmoore Lin, Alioune Ly, Alexander Macharia, Bronwyn MacInnis, Nguyen Mai, Julie Makani, Cinzia Malangone, Valentina Mangano, Alphaxard Manjurano, Lamin Manneh, Laurens Manning, Magnus Manske, Kevin Marsh, Vicki Marsh, Gareth Maslen, Caroline Maxwell, Eric Mbunwe, Marilyn McCreight, Daniel Mead, Alieu Mendy, Anthony Mendy, Nathan Mensah, Pascal Michon, Alistair Miles, Olivo Miotto, David Modiano, Hiba Mohamed, Sile Molloy, Malcolm Molyneux, Sassy Molyneux, Mike Moore, Catherine Moyes, Frank Mtei, George Mtove, Ivo Mueller, Regina Mugri, Annie Munthali, Theonest Mutabingwa, Behzad Nadjm, Andre Ndi, Carolyne Ndila, Charles Newton, Amadou Niangaly, Haddy Njie, Jalimory Njie, Madi Njie, Malick Njie, Sophie Njie, Labes Njiragoma, Francis Nkrumah, Neema Ntunthama, Aceme Nyika, Vysaul Nyirongo, John O'Brien, Herbert Obu, Abraham Oduro, Alex Ofori, Subulade Olaniyan, Rasaq Olaosebikan, Tom Oluoch, Olayemi Omotade, Olajumoke Oni, Emmanuel Onykwelu, Daniel Opi, Adebola Orimadegun, Sean O'Riordan, Issa Ouedraogo, Samuel Oyola, Michael Parker, Richard Pearson, Paul Pensulo, Norbert Peshu, Ajib Phiri, Nguyen Phu, Margaret Pinder, Matti Pirinen, Chris Plowe, Claire Potter, Belco Poudiougou, Odile Puijalon, Nguyen Quyen, Ioannis Ragoussis, Jiannis Ragoussis, Oba Rasheed, John Reeder, Hugh Reyburn, Eleanor Riley, Paul Risley, Kirk Rockett, Joanne Rodford, Jane Rogers, William Rogers, Kate Rowlands, Valentín Ruano-Rubio, Kumba Sabally-Ceesay, Abubacar Sadiq, Momodou Saidy-Khan, Horeja Saine, Anavaj Sakuntabhai, Abdourahmane Sall, David Sambian, Idrissa Sambou, Miguel SanJoaquin, Nuno Sepúlveda, Shivang Shah, Jennifer Shelton, Peter Siba, Nilupa Silva, Cameron Simmons, Jaques Simpore, Pratap Singhasivanon, Dinh Sinh, Sodiomon Sirima, Giorgio Sirugo, Fatoumatta Sisay-Joof, Sibiry Sissoko, Kerrin Small, Elilan Somaskantharajah, Chris Spencer, Jim Stalker, Marryat Stevens, Prapat Suriyaphol, Justice Sylverken, Bintou Taal, Adama Tall, Terrie Taylor, Yik Teo, Cao Thai, Mahamadou Thera, Vincent Titanji, Ousmane Toure, Marita Troye-Blomberg, Stanley Usen, Sophie Uyoga, Aaron Vanderwal, Hannah Wangai, Renee Watson, Thomas Williams, Michael Wilson, Rebecca Wrigley, Clarisse Yafi, Lawrence Yamoah
Categories: malaria news feeds